Synergistic Catalysis for Stereocontrol of Prochiral Nucleophiles in Palladium-Catalyzed Asymmetric Allylic Substitution

Abstract

This review surveys bimetallic catalysis and palladium-organocatalysis strategies for controlling prochiral nucleophiles in asymmetric allylic substitutions, highlighting their role in broadening substrate scope and improving selectivity.

In brief

A review of synergistic strategies for stereocontrol in palladium-catalyzed asymmetric allylic substitution.